Intracellular sodium ion activity and sodium transport in rabbit urinary bladder.

Sodium Chloride Transport by Rabbit

The results of the present study indicate that NaC1 transport by in vitro rabbit gallbladder must be a consequence of a neutral coupled carriermediated mechanism that ultimately results in the active absorption of both ions; pure electrical coupling between the movements of Na and C1 can be excluded on the grounds of electrophysiologic considerations. Studies on the unidirectional influxes of N...

Antibacterial activity of bladder surface mucin duplicated in the rabbit bladder by exogenous glycosaminoglycan (sodium pentosanpolysulfate).

Previous data from our laboratory suggest that the transitional epithelium of the urinary bladder secretes and binds to its surface a glycosaminoglycan. The presence of this substance at the bladder surface markedly reduces the ability of microorganisms to adhere to the mucosa. Furthermore, this glycosaminoglycan can be removed (with acid) and replaced by intravesical instillation of a syntheti...

Sodium ion transport decarboxylases and other aspects of sodium ion cycling in bacteria.

Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry

The cardiac glycoside ouabain inhibits transepithelial sodium transport in the toad urinary bladder. It is shown that this drug reduces the rate coefficient for sodium exit at the serosal pump site. In addition, ouabain inhibits entry across the mucosal border whenever the electrochemical potential gradient for sodium is made less favorable. The data are interpreted as indicating the existence ...

Interactions of sodium transport, cell volume, and calcium in frog urinary bladder

The volume of individual cells in intact frog urinary bladders was determined by quantitative microscopy and changes in volume were used to monitor the movement of solute across the basolateral membrane. When exposed to a serosal hyposmotic solution, the cells swell as expected for an osmometer, but then regulate their volume back to near control in a process that involves the loss of KCl. We s...